| Rank | Movie | Screens | Gross | Year |
|---|
| 1 | Kabali (Tamil & Telugu) | 240 | $3,648,388 | 2016 |
| 2 | Endhiran | 64 | $ 1,520,108 | 2010 |
| 3 | Lingaa [Tamil/Telugu] | 135 | $1,370,000 | 2014 |
| 4 | 24 [Tamil/Telugu] | 155 | $1,076,040 | 2016 |
| 5 | I[Tamil](5 day weekend) | 172 | $697,346 | 2015 |
| 6 | Theri (4 day weekend) | 132 | $643,353 | 2016 |
| 7 | Vishwaroopam[Tamil]
| 43 | $634,912 | 2012 |
| 8 | Sivaji[Tamil]
| 40 | $600,000~ | 2007 |
| 9 | Kaththi (5 day weekend) | 86 | $570,207 | 2014 |
| 10 | Dasavathaaram | 40 | $ 500,000 | 2008 |
| 11 | Yennai Arindhaal(4 day weekend) | 98 | $ 480,432 | 2015 |
| 12 | Uttama Villian | 98 | $ 468,683 | 2015 |
| 13 | OK Kanmani | 65 | $466,564 | 2015 |
| 14 | Kochadaiiyaan [Tamil] | 104 | $436,165 | 2014 |
| 15 | Arrambam (4 day weekend) | 69 | $ 330,615 | 2013 |
| 16 | Thuppakki[Tamil] (6 day weekend) | 36 | $ 277,000 | 2012 |
| 17 | 7am Arivu[Tamil] | 61 | $290,000 ~ | 2011 |
| 18 | Vedalam (6 day weekend) | 71 | $266,786 | 2015 |
| 19 | Billa 2 | 61 | $263,610 | 2013 |
| 20 | Mankatha | 29 | $260,000 | 2011 |
| 21 | Singam II | 46 | $241,926 | 2013 |
| 22 | Masss | 89 | $229,979 | 2015 |
| 23 | Thalaivaa | 70 | $212,000 | 2013 |
| 24 | Papanasam | 80 | $205,426 | 2015 |
| 25 | Veeram | 69 | $202,969 | 2014 |
| 26 | Jilla | 71 | $194,172 | 2014 |
| 27 | Nanban | 50 | $185,000 | 2012 |
| 28 | Raja Rani | 34 | $181,000 | 2012 |
| 29 | Thaandavam | 21 | $183,661 | 2012 |
| 30 | Naanum Rowdy Dhaan (5 day Weekend) | 37 | $178,855 | 2015 |
| 31 | Puli (4 day weekend) | 90 | $175,958 | 2015 |
| 32 | Velaiyilla Pattathari | 21 | $175,500 | 2014 |
| 33 | Mattrraan[Tamil] | - | $170,123 | 2012 |
| 34 | Anjaan[Tamil] | 57 | $162,463 | 2014 |
| 35 | Anegan | 45 | $134,128 | 2015 |
| 36 | Jigarthanda | 20 | $117,746 | 2014 |
| 37 | Velayudam | 22 | $108,000 | 2011 |
| 38 | Deiva Thirumagal | 22 | $104,000 | 2013 |
| 39 | Neethaane En Ponvasantham | - | $92,102 | 2011 |
| 40 | Biriyai | 35 | $85,414 | 2013 |
| 41 | Avan Ivan | 18 | $81,100 | 2011 |
| 42 | IrandamUlagam/Varna | 89 | $75,115 | 2013 |
| 43 | Thani Oruvan | 33 | $74,999 | 2015 |
| 44 | Madras | 34 | $ 73,240 | 2014 |
